Haloperidol

Antipsicótico típico. Antagonista dopaminérgico D2 potente.

1 de fev. de 20261 de

1 cite1×

Gestação:Categoria CRisco não pode ser descartado, usar se benefício justificar

INDICAÇÕES

Adultos

0,5-5mg 2-3x/dia

2-3x/dia

Adultos

2,5-5mg IM/IV

A cada 30min se necessário

Medicamentos que prolongam QTGRAVE

Torsade de pointes

⛔ Evitar, ECG

LevodopaGRAVE

Antagonismo

⛔ Evitar

{"compativel":false,"observacao":"Evitar durante amamentação"}

1 gene with drug interactions

Pharmacogenomics testing may help personalize dosing for this medication. Results depend on patient's genetic profile.

Data source: PharmGKB

Phenotype	Variant	Clinical Implications
Normal/Extensive Metabolizer	1/1, 1/2, 2/2	-Normal drug metabolism -Standard dosing appropriate
Poor Metabolizer	4/4, 4/5, 5/5	-Reduced drug metabolism -Increased drug levels and toxicity risk -Consider dose reduction or alternative drug
Intermediate Metabolizer	1/4, 2/4	-Moderately reduced metabolism -May need dose adjustment
Ultra-rapid Metabolizer	1/1xN, 2/2xN	-Rapid drug metabolism -Reduced drug efficacy -May need increased dose or alternative drug